What GHK-Cu is
GHK-Cu is the copper(II) complex of glycyl-L-histidyl-L-lysine, a tripeptide first isolated from plasma in the 1970s and noted for its very high affinity for copper ions. Copper is held by the glycine amine, the adjacent backbone nitrogen and the histidine imidazole, with lysine's long side chain left free. GHK-Cu is one of the most widely studied copper peptides in cell-culture and skin-biology research, and it is also listed in cosmetic ingredient databases as copper tripeptide-1.
GHK-Cu Labs supplies it as a blue lyophilized powder in 50 mg and 100 mg vials. Each lot is tested by an independent laboratory for HPLC-UV purity, LC-MS identity and net content, and the full certificate is published here before sale through Klow.bio.
Structure
The tripeptide Gly-His-Lys has a free N-terminus and free C-terminal acid. The formula and molecular weight given (C14H24N6O4, 340.38 g/mol) are for the peptide alone; the complex adds one copper(II) ion, and the salt form depends on preparation. The blue color comes from the bound copper.
complete GHK-Cu specifications.
Storage and handling
Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. Lyophilized material absorbs moisture from the air, and absorbed moisture restarts the reactions that drying slows, so keep vials sealed until needed. Storage and stability guide.