GHK-Cu specifications and molecular characteristics
The technical specification for GHK-Cu, the GHK-Cu research material supplied by GHK-Cu Labs: molecular formula C14H24N6O4 (GHK peptide, without copper), average molecular weight 340.38 g/mol, 3 residues, supplied as a blue lyophilized powder. Each item is explained below.
Last updated
Specification table
| Product | GHK-Cu |
|---|---|
| Type | Copper(II) complex of the tripeptide Gly-His-Lys |
| Molecular formula (GHK peptide, without copper) | C14H24N6O4 |
| Molecular weight (GHK peptide, without copper) | 340.38 g/mol (average) |
| Length | 3 residues |
| Sequence | GHK |
| Metal | Copper(II) |
| Peptide | Gly-His-Lys (free acid) |
| Appearance | Blue lyophilized powder |
| Form | Blue lyophilized powder |
| Vial sizes | 50 mg, 100 mg |
| Purity specification | ≥95% (HPLC-UV) |
| Purity, current lots | 99.81% |
| Identity specification | Confirmed by LC-MS |
| Testing laboratory | Freedom Diagnostics (independent) |
| Storage | Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. |
| Designation | Research use only |
Current lot results against specification
Every current lot meets the release specification. Current lots test at 99.81% by HPLC-UV against a specification of ≥95%, and identity is confirmed by LC-MS on every lot.
GHK-Cu molecular formula
The molecular formula of GHK peptide, without copper is C14H24N6O4.
GHK-Cu molecular weight
The average molecular weight of GHK peptide, without copper is 340.38 g/mol. "Average" means it is calculated from natural isotope abundances, which is the value used to predict the ions seen in LC-MS. With this weight, GHK-Cu is expected at m/z 341.4 with one charge and m/z 171.2 with two charges.
GHK-Cu sequence
GHK
Structure and modifications
The tripeptide Gly-His-Lys has a free N-terminus and free C-terminal acid. The formula and molecular weight given (C14H24N6O4, 340.38 g/mol) are for the peptide alone; the complex adds one copper(II) ion, and the salt form depends on preparation. The blue color comes from the bound copper.
Physical form
Blue lyophilized powder, recorded as the appearance on every certificate. Lyophilization (freeze-drying) removes water, which slows most chemical degradation. What lyophilized means.
Purity and identity specifications
GHK-Cu Labs’ stated release specification is ≥95% HPLC-UV purity with identity confirmed by LC-MS. The current lot, KB10020, reported 99.81%. How purity is measured, or how specifications fit into the quality and supply-chain process.
Analytical and testing methods
HPLC-UV for purity, LC-MS for identity and laboratory quantitation for net content, performed on every lot by Freedom Diagnostics. LAL endotoxin testing (USP <85>) and PCR microbial screening are reported for lots where they were run. Testing and quality control.
Research designation
GHK-Cu is designated research use only: supplied for laboratory research by qualified personnel. Research use only policy.
Buy GHK-Cu
50 mg and 100 mg vials. Current lot KB10020 tested at 99.81% purity with identity confirmed by LC-MS. Current purchasing is available through Klow.bio.